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The IntelliCyt® iQue Screener PLUS platform integrates a flow based instrument with enabling and easy to use software and reagents designed to address key challenges across the suspension-cell screening workflow.
Rapid high
content suspension cell screening
The IntelliCyt® iQue Screener PLUS platform integrates a
flow based instrument with enabling and easy to use software and reagents
designed to address key challenges across the suspension-cell screening
workflow. The platform allows researchers to acquire and analyze high content,
multiplexed assays needed to assess immune cell function by combining cell
immuno-phenotyping, cell health, and secreted protein (cytokine) analysis in
every well of a microtiter plate.
Whether working with a few or thousands of samples, the
heart of the IntelliCyt platform is its powerful ForeCyt® Software that
provides an intuitive and comprehensive analysis and visualization environment
to quickly turn multi-parameter data into straightforward, actionable results.
From linking well data to combining multiple assay outcomes together to
expedite identification of leads, ForeCyt® software streamlines your analysis
workflow by providing cell, well, plate and experiment level data at your
fingertips thus enabling you to get to insights that drive drug discovery.
Multiplex Phenotype and Function from Less Sample in Record
Time Intellicyt® iQue Screener PLUS
Speed to
actionable results from every well
The Intellicyt iQue Screener PLUS platform is an integrated
instrument, software, and reagent system that enables simultaneous evaluation
of cells and proteins using less sample while providing actionable
multi-parametric data in record time.
While standard flow cytometry is commonly used to identify
and characterize cells and beads in solution. It has limitations in assay
throughput, automated data analysis capabilities, sample/reagent volume
requirements, and ease-of-use. The Intellicyt iQue Screener PLUS platform
addresses these limitations with these advantages:
Speed
Relieve capacity bottlenecks with the fastest plate
sampling, integrated analysis, multiplexed no-wash assays, and novel data
reduction tools.
Miniaturization
Conserve precious samples and reagents by sampling as little
as a single microliter from miniaturized assay volumes.
Content
Perform high content, multiplexed analysis of cells, beads
and secreted proteins in suspension.
Usability
Enjoy a simple, scalable, multi-user environment with
walkaway automation, comprehensive analysis and visualization tools, and other
features not found in traditional solutions.
Insight
Dramatically reduce time to decision with novel
visualizations that facilitate the fastest path to actionable results, even
from complex data sets.
The
Intellicyt iQue Screener PLUS Accelerates Your Research
·
Rapid, Walkaway Plate Processing
·
Patented, rapid microvolume sampling processes
96 well plates in as few as 5 minutes or 384 well plates in 20 minutes.
·
Samples are delivered to detectors in an air-gap
delimited stream, so an entire plate of data can be processed at one time.
·
Generous cartridge station allows for unattended
multiple plate processing.
·
Interface and integration development kit allows
easy use of your favorite automation.
·
Assay protocols are configurable for any point
during or after plate sampling.
·
Perform routine tasks with the touch of a
button, including system cleaning, plate map calibration, shutdown, and even
fluidics refilling (with the QMax Refill Module).
Real-time
Data Acquisition and Analysis and Dynamic Visualization of Results
Rapid assay
optimization – adjust a gate to see updated plate-wide analysis in real time.
·
Easy, interactive assay development and decision
environment that is reproducible across plates.
·
Plate level annotation, analysis, and
visualization integrated within the standard population selection tools.
The
Intellicyt iQue Screener PLUS comes in multiple optical configurations and
flexible plate formats
Configuration |
Blue-Red |
Violet-Blue-Red |
Violet-Yellow-Blue |
Lasers |
488nm, 640nm |
405nm, 488nm, 640nm |
405nm, 561nm, 488nm |
Detection Channels |
8 |
15 |
15 |
Plate Types |
96- and 384-well, 384- and 1536-well (Blue-Red HD) |
96- and 384-well |
96- and 384-well |
Min Sampling Time |
< 5 minutes/96 wells, < 20 minutes/384 wells |
||
Min Sample Aspiration |
1 µL |
||
Detection Rate |
Up to 35,000 events/second |
||
Dynamic Range |
> 7 Decades |